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Stim-activated TRPC-ORAI channels in pulmonary hypertension induced by chronic intermittent hypoxia

Obstructive sleep apnea (OSA), a breathing disorder featured by chronic intermittent hypoxia (CIH) is associated with pulmonary hypertension (PH). Rodents exposed to CIH develop pulmonary vascular remodeling and PH, but the pathogenic mechanisms are not well known. Overexpression of Stim-activated T...

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Detalles Bibliográficos
Autores principales: Castillo-Galán, Sebastian, Arenas, German A., Reyes, Roberto V., Krause, Bernardo J., Iturriaga, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557718/
https://www.ncbi.nlm.nih.gov/pubmed/33110495
http://dx.doi.org/10.1177/2045894020941484