Transferrin Non-Viral Gene Therapy for Treatment of Retinal Degeneration

Dysregulation of iron metabolism is observed in animal models of retinitis pigmentosa (RP) and in patients with age-related macular degeneration (AMD), possibly contributing to oxidative damage of the retina. Transferrin (TF), an endogenous iron chelator, was proposed as a therapeutic candidate. Her...

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Detalles Bibliográficos
Autores principales: Bigot, Karine, Gondouin, Pauline, Bénard, Romain, Montagne, Pierrick, Youale, Jenny, Piazza, Marie, Picard, Emilie, Bordet, Thierry, Behar-Cohen, Francine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557784/
https://www.ncbi.nlm.nih.gov/pubmed/32882879
http://dx.doi.org/10.3390/pharmaceutics12090836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557784/
https://www.ncbi.nlm.nih.gov/pubmed/32882879
http://dx.doi.org/10.3390/pharmaceutics12090836

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