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Impact of Albumin and Omeprazole on Steady-State Population Pharmacokinetics of Voriconazole and Development of a Voriconazole Dosing Optimization Model in Thai Patients with Hematologic Diseases

This study aimed to identify factors that significantly influence the pharmacokinetics of voriconazole in Thai adults with hematologic diseases, and to determine optimal voriconazole dosing regimens. Blood samples were collected at steady state in 65 patients (237 concentrations) who were taking vor...

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Detalles Bibliográficos
Autores principales: Khan-asa, Buddharat, Punyawudho, Baralee, Singkham, Noppaket, Chaivichacharn, Piyawat, Karoopongse, Ekapun, Montakantikul, Preecha, Chayakulkeeree, Methee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557832/
https://www.ncbi.nlm.nih.gov/pubmed/32899425
http://dx.doi.org/10.3390/antibiotics9090574