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Improving the Solubility and Bioavailability of Pemafibrate via a New Polymorph Form II
[Image: see text] Pemafibrate is a new generation of anti-hyperlipidemia drugs. However, its poor solubility in water (0.410 mg/mL at 25 °C) has limited its oral bioavailability. In this study, we aimed to improve the solubility and consequently the oral bioavailability of pemafibrate via a new poly...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557989/ https://www.ncbi.nlm.nih.gov/pubmed/33073151 http://dx.doi.org/10.1021/acsomega.0c04005 |