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Pyrido-Fused Deazapurine Bases: Synthesis and Glycosylation of 4-Substituted 9H-Pyrido[2′,3′:4,5]- and Pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidines

[Image: see text] Two isomeric sets of 4-substituted pyridopyrrolopyrimidine nucleobases were prepared through nucleophilic substitutions or cross-coupling reactions of 4-chloropyridopyrrolopyrimidines. The corresponding 4-amino-pyridopyrrolopyrimidines were glycosylated with 5-O-tritylribose using...

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Detalles Bibliográficos
Autores principales: Veselovská, Lucia, Pohl, Radek, Tloušt′ová, Eva, Gurská, Soňa, Džubák, Petr, Hajdúch, Marián, Hocek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557996/
https://www.ncbi.nlm.nih.gov/pubmed/33073155
http://dx.doi.org/10.1021/acsomega.0c04302