Sortase-Mediated Site-Specific Modification of Interleukin-2 for the Generation of a Tumor-Targeting Acetazolamide–Cytokine Conjugate

[Image: see text] Small ligands specific to tumor-associated antigens can be used as alternatives to antibodies for the delivery of small payloads such as radionuclides, cytotoxic drugs, and fluorophores. Their use as a delivery moiety of bioactive proteins such as cytokines remains largely unexplor...

Descripción completa

Detalles Bibliográficos
Autores principales: Gouyou, Baptiste, Millul, Jacopo, Villa, Alessandra, Cazzamalli, Samuele, Neri, Dario, Matasci, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558062/
https://www.ncbi.nlm.nih.gov/pubmed/33073134
http://dx.doi.org/10.1021/acsomega.0c03592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558062/
https://www.ncbi.nlm.nih.gov/pubmed/33073134
http://dx.doi.org/10.1021/acsomega.0c03592

Ejemplares similares