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Protein Expression Knockdown in Cancer Cells Induced by a Gemini Cationic Lipid Nanovector with Histidine-Based Polar Heads

A histidine-based gemini cationic lipid, which had already demonstrated its efficiency as a plasmid DNA (pDNA) nanocarrier, has been used in this work to transfect a small interfering RNA (siRNA) into cancer cells. In combination with the helper lipid monoolein glycerol (MOG), the cationic lipid was...

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Detalles Bibliográficos
Autores principales: Sánchez-Arribas, Natalia, Martínez-Negro, María, Villar, Eva M., Pérez, Lourdes, Osío Barcina, José, Aicart, Emilio, Taboada, Pablo, Guerrero-Martínez, Andrés, Junquera, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558209/
https://www.ncbi.nlm.nih.gov/pubmed/32825658
http://dx.doi.org/10.3390/pharmaceutics12090791