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Pharmacokinetics of Shikimic Acid Following Intragastric and Intravenous Administrations in Rats

Shikimic acid, a critical starting material for the semi-total synthesis of oseltamivir to treat and prevent influenza, exerts many pharmacological effects. However, the optimal bioanalytical method has not been adequately defined. We used liquid chromatography-tandem mass spectrometry to quantitate...

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Detalles Bibliográficos
Autores principales: Noh, Keumhan, Back, Hyun-Moon, Shin, Beom Soo, Kang, Wonku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558350/
https://www.ncbi.nlm.nih.gov/pubmed/32872397
http://dx.doi.org/10.3390/pharmaceutics12090824