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Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer’s Disease

Extracellular amyloid-beta deposition and intraneuronal Tau-laden neurofibrillary tangles are prime features of Alzheimer’s disease (AD). The pathology of AD is very complex and still not fully understood, since different neural cell types are involved in the disease. Although neuronal function is c...

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Detalles Bibliográficos
Autores principales: Garcia-Leon, Juan Antonio, Caceres-Palomo, Laura, Sanchez-Mejias, Elisabeth, Mejias-Ortega, Marina, Nuñez-Diaz, Cristina, Fernandez-Valenzuela, Juan Jose, Sanchez-Varo, Raquel, Davila, Jose Carlos, Vitorica, Javier, Gutierrez, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558359/
https://www.ncbi.nlm.nih.gov/pubmed/32962164
http://dx.doi.org/10.3390/ijms21186867