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Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer’s Disease
Extracellular amyloid-beta deposition and intraneuronal Tau-laden neurofibrillary tangles are prime features of Alzheimer’s disease (AD). The pathology of AD is very complex and still not fully understood, since different neural cell types are involved in the disease. Although neuronal function is c...
Autores principales: | Garcia-Leon, Juan Antonio, Caceres-Palomo, Laura, Sanchez-Mejias, Elisabeth, Mejias-Ortega, Marina, Nuñez-Diaz, Cristina, Fernandez-Valenzuela, Juan Jose, Sanchez-Varo, Raquel, Davila, Jose Carlos, Vitorica, Javier, Gutierrez, Antonia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558359/ https://www.ncbi.nlm.nih.gov/pubmed/32962164 http://dx.doi.org/10.3390/ijms21186867 |
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