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Efficacy of Emu Oil Transfersomes for Local Transdermal Delivery of 4-OH Tamoxifen in the Treatment of Breast Cancer

Oral tamoxifen used in the prevention and treatment of ductal carcinoma in situ (DCIS) (estrogen-positive) patients has limited acceptance, due to its adverse side effects. The efficacy of tamoxifen is related to its major metabolite, 4-hydroxytamoxifen. Local transdermal therapy of 4-hydroxytamoxif...

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Detalles Bibliográficos
Autores principales: Sundralingam, Usha, Chakravarthi, Srikumar, Radhakrishnan, Ammu Kutty, Muniyandy, Saravanan, Palanisamy, Uma D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558379/
https://www.ncbi.nlm.nih.gov/pubmed/32854385
http://dx.doi.org/10.3390/pharmaceutics12090807