The Possible Contribution of P-Glycoprotein in the Protective Effect of Paeonol against Methotrexate-Induced Testicular Injury in Rats

Paeonol, a phenolic ingredient in the genus Paeonia, possesses antioxidant and anti-inflammatory effects. Methotrexate (MTX) is a commonly used chemotherapeutic agent; however, its germ cell damage is a critical problem. P-glycoprotein (P-gp), an efflux transporter, is a member of the blood–testis b...

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Detalles Bibliográficos
Autores principales: Morsy, Mohamed A., Abdel-Aziz, Asmaa M., Abdel-Hafez, Sara M. N., Venugopala, Katharigatta N., Nair, Anroop B., Abdel-Gaber, Seham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558391/
https://www.ncbi.nlm.nih.gov/pubmed/32872504
http://dx.doi.org/10.3390/ph13090223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558391/
https://www.ncbi.nlm.nih.gov/pubmed/32872504
http://dx.doi.org/10.3390/ph13090223

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