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Antibody–Drug Conjugates: The Last Decade

An armed antibody (antibody–drug conjugate or ADC) is a vectorized chemotherapy, which results from the grafting of a cytotoxic agent onto a monoclonal antibody via a judiciously constructed spacer arm. ADCs have made considerable progress in 10 years. While in 2009 only gemtuzumab ozogamicin (Mylot...

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Detalles Bibliográficos
Autores principales: Joubert, Nicolas, Beck, Alain, Dumontet, Charles, Denevault-Sabourin, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558467/
https://www.ncbi.nlm.nih.gov/pubmed/32937862
http://dx.doi.org/10.3390/ph13090245