In Vitro Metabolism of DWP16001, a Novel Sodium-Glucose Cotransporter 2 Inhibitor, in Human and Animal Hepatocytes

DWP16001 is currently in a phase 2 clinical trial as a novel anti-diabetes drug for the treatment of type 2 diabetes by selective inhibition of sodium-glucose cotransporter 2. This in vitro study was performed to compare the metabolism of DWP16001 in human, dog, monkey, mouse, and rat hepatocytes, a...

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Detalles Bibliográficos
Autores principales: Kim, Ju-Hyun, Kim, Dong Kyun, Choi, Won-Gu, Ji, Hye-Young, Choi, Ji-Soo, Song, Im-Sook, Lee, Sangkyu, Lee, Hye Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558535/
https://www.ncbi.nlm.nih.gov/pubmed/32932946
http://dx.doi.org/10.3390/pharmaceutics12090865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558535/
https://www.ncbi.nlm.nih.gov/pubmed/32932946
http://dx.doi.org/10.3390/pharmaceutics12090865

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