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Docetaxel-Loaded Chitosan-Cholesterol Conjugate-Based Self-Assembled Nanoparticles for Overcoming Multidrug Resistance in Cancer Cells

Cholesteryl hemisuccinate (CHS)-conjugated chitosan (CS)-based self-assembled nanoparticles (NPs) were developed for enhancing the intracellular uptake of docetaxel in multidrug resistance (MDR)-acquired cancer cells. CHS-CS was successfully synthesized and self-aggregation, particle size, zeta pote...

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Detalles Bibliográficos
Autores principales: Mu, Chao-Feng, Cui, Fude, Yin, Yong-Mei, Cho, Hyun-Jong, Kim, Dae-Duk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558660/
https://www.ncbi.nlm.nih.gov/pubmed/32825000
http://dx.doi.org/10.3390/pharmaceutics12090783