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Microbiota Imbalance Contributes to COPD Deterioration by Enhancing IL-17a Production via miR-122 and miR-30a

The changes of microbiota in lungs could change interleukin-17a (IL-17a) expression by altering microRNAs (miRNAs) profile, thus contributing to the pathogenesis of chronic obstructive pulmonary disease (COPD). In this study, we aimed to study molecular mechanisms’ underlying effect of microbiota im...

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Detalles Bibliográficos
Autores principales: Zhu, Ke, Zhou, Sijing, Xu, Aiqun, Sun, Li, Li, Min, Jiang, Huihui, Zhang, Binbin, Zeng, Daxiong, Fei, Guanghe, Wang, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558803/
https://www.ncbi.nlm.nih.gov/pubmed/33230454
http://dx.doi.org/10.1016/j.omtn.2020.09.017