WAS Promoter-Driven Lentiviral Vectors Mimic Closely the Lopsided WASP Expression during Megakaryocytic Differentiation

Transplant of gene-modified autologous hematopoietic progenitors cells has emerged as a new therapeutic approach for Wiskott-Aldrich syndrome (WAS), a primary immunodeficiency with microthrombocytopenia and abnormal lymphoid and myeloid functions. Despite the clinical benefits obtained in ongoing cl...

Descripción completa

Detalles Bibliográficos
Autores principales: Muñoz, Pilar, Tristán-Manzano, María, Sánchez-Gilabert, Almudena, Santilli, Giorgia, Galy, Anne, Thrasher, Adrian J., Martin, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558809/
https://www.ncbi.nlm.nih.gov/pubmed/33102615
http://dx.doi.org/10.1016/j.omtm.2020.09.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558809/
https://www.ncbi.nlm.nih.gov/pubmed/33102615
http://dx.doi.org/10.1016/j.omtm.2020.09.006

Ejemplares similares