Role of OATP1B1 and OATP1B3 in Drug-Drug Interactions Mediated by Tyrosine Kinase Inhibitors

Failure to recognize important features of a drug’s pharmacokinetic characteristics is a key cause of inappropriate dose and schedule selection, and can lead to reduced efficacy and increased rate of adverse drug reactions requiring medical intervention. As oral chemotherapeutic agents, tyrosine kin...

Descripción completa

Detalles Bibliográficos
Autores principales: Garrison, Dominique A., Talebi, Zahra, Eisenmann, Eric D., Sparreboom, Alex, Baker, Sharyn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559291/
https://www.ncbi.nlm.nih.gov/pubmed/32916864
http://dx.doi.org/10.3390/pharmaceutics12090856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559291/
https://www.ncbi.nlm.nih.gov/pubmed/32916864
http://dx.doi.org/10.3390/pharmaceutics12090856

Ejemplares similares