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Role of OATP1B1 and OATP1B3 in Drug-Drug Interactions Mediated by Tyrosine Kinase Inhibitors

Failure to recognize important features of a drug’s pharmacokinetic characteristics is a key cause of inappropriate dose and schedule selection, and can lead to reduced efficacy and increased rate of adverse drug reactions requiring medical intervention. As oral chemotherapeutic agents, tyrosine kin...

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Detalles Bibliográficos
Autores principales:	Garrison, Dominique A., Talebi, Zahra, Eisenmann, Eric D., Sparreboom, Alex, Baker, Sharyn D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559291/ https://www.ncbi.nlm.nih.gov/pubmed/32916864 http://dx.doi.org/10.3390/pharmaceutics12090856

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