Serial Passage of Cryptococcus neoformans in Galleria mellonella Results in Increased Capsule and Intracellular Replication in Hemocytes, but Not Increased Resistance to Hydrogen Peroxide

To gain insight into how pathogens adapt to new hosts, Cryptococcus neoformans (H99W) was serially passaged in Galleria mellonella. The phenotypic characteristics of the passaged strain (P15) and H99W were evaluated. P15 grew faster in hemolymph than H99W, in vitro and in vivo, suggesting that adapt...

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Detalles Bibliográficos
Autores principales: Ali, Muhammad Fariz, Tansie, Stephen M., Shahan, John R., Seipelt-Thiemann, Rebecca L., McClelland, Erin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559301/
https://www.ncbi.nlm.nih.gov/pubmed/32899539
http://dx.doi.org/10.3390/pathogens9090732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559301/
https://www.ncbi.nlm.nih.gov/pubmed/32899539
http://dx.doi.org/10.3390/pathogens9090732

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