Complement Properdin Determines Disease Activity in MRL/lpr Mice

Background and objects: In systemic lupus erythematosus, circulating immune complexes activate complement and, when trapped in renal capillaries, cause glomerulonephritis. Mouse models have been used in the preclinical assessment of targeting complement activation pathways to manage chronic inflamma...

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Detalles Bibliográficos
Autores principales: Alaridhee, Hasanain, Alharbi, Azzah, Saeed, Zeayd, Thomas, Róisín C., Stover, Cordula M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559332/
https://www.ncbi.nlm.nih.gov/pubmed/32867176
http://dx.doi.org/10.3390/medicina56090430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559332/
https://www.ncbi.nlm.nih.gov/pubmed/32867176
http://dx.doi.org/10.3390/medicina56090430

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