Understanding the Half-Life Extension of Intravitreally Administered Antibodies Binding to Ocular Albumin

The burden associated with frequent injections of current intravitreal (IVT) therapeutics may be reduced by long-acting delivery strategies. Binding to serum albumin has been shown to extend the ocular half-life in rabbits, however, the underlying molecular mechanisms and translational relevance rem...

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Detalles Bibliográficos
Autores principales: Hauri, Simon, Jakubiak, Paulina, Fueth, Matthias, Dengl, Stefan, Belli, Sara, Alvarez-Sánchez, Rubén, Caruso, Antonello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559355/
https://www.ncbi.nlm.nih.gov/pubmed/32858986
http://dx.doi.org/10.3390/pharmaceutics12090810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559355/
https://www.ncbi.nlm.nih.gov/pubmed/32858986
http://dx.doi.org/10.3390/pharmaceutics12090810

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