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Do Ophthalmic Solutions of Amphotericin B Solubilised in 2-Hydroxypropyl-γ-Cyclodextrins Possess an Extended Physicochemical Stability?

Fungal keratitis is a sight-threatening disease for which amphotericin B eye drops is one of the front-line treatments. Unfortunately, there are currently no commercial forms available, and there is little data concerning the long-term stability of compounded formulations based on intravenous dosage...

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Detalles Bibliográficos
Autores principales: Chennell, Philip, Yessaad, Mouloud, Abd El Kader, Florence, Jouannet, Mireille, Wasiak, Mathieu, Bouattour, Yassine, Sautou, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559369/
https://www.ncbi.nlm.nih.gov/pubmed/32825121
http://dx.doi.org/10.3390/pharmaceutics12090786