Optimization and Evaluation of Poly(lactide-co-glycolide) Nanoparticles for Enhanced Cellular Uptake and Efficacy of Paclitaxel in the Treatment of Head and Neck Cancer

The particle size (PS) and encapsulation efficiency (EE%) of drug-loaded nanoparticles (NPs) may inhibit their cellular uptake and lead to possible leakage of the drug into the systemic circulation at the tumor site. In this work, ultra-high paclitaxel-loaded poly(lactide-co-glycolide) NPs (PTX-PLGA...

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Detalles Bibliográficos
Autores principales: Haider, Mohamed, Elsherbeny, Amr, Jagal, Jayalakshmi, Hubatová-Vacková, Anna, Saad Ahmed, Iman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559439/
https://www.ncbi.nlm.nih.gov/pubmed/32872639
http://dx.doi.org/10.3390/pharmaceutics12090828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559439/
https://www.ncbi.nlm.nih.gov/pubmed/32872639
http://dx.doi.org/10.3390/pharmaceutics12090828

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