Zinc Binding by Histatin 5 Promotes Fungicidal Membrane Disruption in C. albicans and C. glabrata

Histatin 5 (Hst 5) is an antimicrobial peptide produced in human saliva with antifungal activity for opportunistic pathogen Candida albicans. Hst 5 binds to multiple cations including dimerization-inducing zinc (Zn(2+)), although the function of this capability is incompletely understood. Hst 5 is t...

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Detalles Bibliográficos
Autores principales: Norris, Hannah L., Kumar, Rohitashw, Ong, Chih Yean, Xu, Ding, Edgerton, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559477/
https://www.ncbi.nlm.nih.gov/pubmed/32751915
http://dx.doi.org/10.3390/jof6030124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559477/
https://www.ncbi.nlm.nih.gov/pubmed/32751915
http://dx.doi.org/10.3390/jof6030124

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