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Zinc Binding by Histatin 5 Promotes Fungicidal Membrane Disruption in C. albicans and C. glabrata
Histatin 5 (Hst 5) is an antimicrobial peptide produced in human saliva with antifungal activity for opportunistic pathogen Candida albicans. Hst 5 binds to multiple cations including dimerization-inducing zinc (Zn(2+)), although the function of this capability is incompletely understood. Hst 5 is t...
Autores principales: | Norris, Hannah L., Kumar, Rohitashw, Ong, Chih Yean, Xu, Ding, Edgerton, Mira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559477/ https://www.ncbi.nlm.nih.gov/pubmed/32751915 http://dx.doi.org/10.3390/jof6030124 |
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