Effect of Different Direct Compaction Grades of Mannitol on the Storage Stability of Tablet Properties Investigated Using a Kohonen Self-Organizing Map and Elastic Net Regression Model

This study tested 15 direct compaction grades to identify the contribution of different grades of mannitol to the storage stability of the resulting tablets. After preparing the model tablets with different values of hardness, they were stored at 25 °C, 75% relative humidity for 1 week. Then, measur...

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Detalles Bibliográficos
Autores principales: Kosugi, Atsushi, Leong, Kok Hoong, Urata, Eri, Hayashi, Yoshihiro, Kumada, Shungo, Okada, Kotaro, Onuki, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559487/
https://www.ncbi.nlm.nih.gov/pubmed/32961856
http://dx.doi.org/10.3390/pharmaceutics12090886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559487/
https://www.ncbi.nlm.nih.gov/pubmed/32961856
http://dx.doi.org/10.3390/pharmaceutics12090886

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