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Pharmacokinetic Comparison of Three Different Administration Routes for Topotecan Hydrochloride in Rats

Topotecan is actively used in clinic, with its primary use being in treatment of various types of cancer. The approved administration routes are oral and intravenous. The purpose of this study was to investigate and identify pharmacokinetic profiles of different administration routes. We conducted p...

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Detalles Bibliográficos
Autores principales: Jeong, Seung-Hyun, Jang, Ji-Hun, Lee, Yong-Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559546/
https://www.ncbi.nlm.nih.gov/pubmed/32887301
http://dx.doi.org/10.3390/ph13090231