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Pharmacokinetic Comparison of Three Different Administration Routes for Topotecan Hydrochloride in Rats
Topotecan is actively used in clinic, with its primary use being in treatment of various types of cancer. The approved administration routes are oral and intravenous. The purpose of this study was to investigate and identify pharmacokinetic profiles of different administration routes. We conducted p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559546/ https://www.ncbi.nlm.nih.gov/pubmed/32887301 http://dx.doi.org/10.3390/ph13090231 |