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In Vivo Validation of Spray-Dried Mesoporous Bioactive Glass Microspheres Acting as Prolonged Local Release Systems for BMP-2 to Support Bone Regeneration

Bone morphogenetic protein-2 (BMP-2) is a known key mediator of physiological bone regeneration and is clinically approved for selected musculoskeletal interventions. Yet, broad usage of this growth factor is impeded due to side effects that are majorly evoked by high dosages and burst release kinet...

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Detalles Bibliográficos
Autores principales: Berkmann, Julia C., Herrera Martin, Aaron X., Pontremoli, Carlotta, Zheng, Kai, Bucher, Christian H., Ellinghaus, Agnes, Boccaccini, Aldo R., Fiorilli, Sonia, Vitale Brovarone, Chiara, Duda, Georg N., Schmidt-Bleek, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559713/
https://www.ncbi.nlm.nih.gov/pubmed/32872353
http://dx.doi.org/10.3390/pharmaceutics12090823