Encapsulation of Nedaplatin in Novel PEGylated Liposomes Increases Its Cytotoxicity and Genotoxicity against A549 and U2OS Human Cancer Cells

Following the discovery of cisplatin over 50 years ago, platinum-based drugs have been a widely used and effective form of cancer therapy, primarily causing cell death by inducing DNA damage and triggering apoptosis. However, the dose-limiting toxicity of these drugs has led to the development of se...

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Detalles Bibliográficos
Autores principales: El-Shafie, Salma, Fahmy, Sherif Ashraf, Ziko, Laila, Elzahed, Nada, Shoeib, Tamer, Kakarougkas, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559812/
https://www.ncbi.nlm.nih.gov/pubmed/32927897
http://dx.doi.org/10.3390/pharmaceutics12090863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559812/
https://www.ncbi.nlm.nih.gov/pubmed/32927897
http://dx.doi.org/10.3390/pharmaceutics12090863

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