Cargando…

Functional and Pharmacological Comparison of Human, Mouse, and Rat Organic Cation Transporter 1 toward Drug and Pesticide Interaction

Extrapolation from animal to human data is not always possible, because several essential factors, such as expression level, localization, as well as the substrate selectivity and affinity of relevant transport proteins, can differ between species. In this study, we examined the interactions of drug...

Descripción completa

Detalles Bibliográficos
Autores principales: Floerl, Saskia, Kuehne, Annett, Hagos, Yohannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559834/
https://www.ncbi.nlm.nih.gov/pubmed/32961667
http://dx.doi.org/10.3390/ijms21186871