Cargando…
Functional and Pharmacological Comparison of Human, Mouse, and Rat Organic Cation Transporter 1 toward Drug and Pesticide Interaction
Extrapolation from animal to human data is not always possible, because several essential factors, such as expression level, localization, as well as the substrate selectivity and affinity of relevant transport proteins, can differ between species. In this study, we examined the interactions of drug...
Autores principales: | Floerl, Saskia, Kuehne, Annett, Hagos, Yohannes |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559834/ https://www.ncbi.nlm.nih.gov/pubmed/32961667 http://dx.doi.org/10.3390/ijms21186871 |
Ejemplares similares
-
Investigations with Drugs and Pesticides Revealed New Species- and Substrate-Dependent Inhibition by Elacridar and Imazalil in Human and Mouse Organic Cation Transporter OCT2
por: Kuehne, Annett, et al.
Publicado: (2022) -
Interaction of the New Monofunctional Anticancer Agent Phenanthriplatin With Transporters for Organic Cations
por: Hucke, Anna, et al.
Publicado: (2018) -
Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations
por: Ciarimboli, Giuliano
Publicado: (2021) -
Organic Cation Transporters in Human Physiology, Pharmacology, and Toxicology
por: Samodelov, Sophia L., et al.
Publicado: (2020) -
Physiology, Biochemistry and Pharmacology of Transporters for Organic Cations 2.0
por: Ciarimboli, Giuliano
Publicado: (2022)