A cancer-specific anti-podocalyxin monoclonal antibody (60-mG(2a)-f) exerts antitumor effects in mouse xenograft models of pancreatic carcinoma

Overexpression of podocalyxin (PODXL) is associated with progression, metastasis, and poor outcomes in several cancers. PODXL also plays an important role in the development of normal tissues. For antibody-based therapy to target PODXL-expressing cancers using monoclonal antibodies (mAbs), cancer-sp...

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Detalles Bibliográficos
Autores principales: Kaneko, Mika K., Ohishi, Tomokazu, Kawada, Manabu, Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559861/
https://www.ncbi.nlm.nih.gov/pubmed/33088928
http://dx.doi.org/10.1016/j.bbrep.2020.100826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559861/
https://www.ncbi.nlm.nih.gov/pubmed/33088928
http://dx.doi.org/10.1016/j.bbrep.2020.100826

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