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Efficient Transfection of Large Plasmids Encoding HIV-1 into Human Cells—A High Potential Transfection System Based on a Peptide Mimicking Cationic Lipid

One major disadvantage of nucleic acid delivery systems is the low transfection or transduction efficiency of large-sized plasmids into cells. In this communication, we demonstrate the efficient transfection of a 15.5 kb green fluorescent protein (GFP)-fused HIV-1 molecular clone with a nucleic acid...

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Detalles Bibliográficos
Autores principales: Janich, Christopher, Ivanusic, Daniel, Giselbrecht, Julia, Janich, Elena, Pinnapireddy, Shashank Reddy, Hause, Gerd, Bakowsky, Udo, Langner, Andreas, Wölk, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559901/
https://www.ncbi.nlm.nih.gov/pubmed/32854383
http://dx.doi.org/10.3390/pharmaceutics12090805