In Vitro Modeling of Bradykinin-Mediated Angioedema States

Kinins (peptides related to bradykinin, BK) are formed from circulating substrates, the kininogens, by the action of two proteases, the kallikreins. The only clinical application of a BK receptor ligand, the B(2) receptor antagonist icatibant, is the treatment of the rare hereditary angioedema (HAE)...

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Detalles Bibliográficos
Autores principales: Marceau, François, Bachelard, Hélène, Charest-Morin, Xavier, Hébert, Jacques, Rivard, Georges E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559923/
https://www.ncbi.nlm.nih.gov/pubmed/32824891
http://dx.doi.org/10.3390/ph13090201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559923/
https://www.ncbi.nlm.nih.gov/pubmed/32824891
http://dx.doi.org/10.3390/ph13090201

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