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In Vitro Modeling of Bradykinin-Mediated Angioedema States
Kinins (peptides related to bradykinin, BK) are formed from circulating substrates, the kininogens, by the action of two proteases, the kallikreins. The only clinical application of a BK receptor ligand, the B(2) receptor antagonist icatibant, is the treatment of the rare hereditary angioedema (HAE)...
Autores principales: | Marceau, François, Bachelard, Hélène, Charest-Morin, Xavier, Hébert, Jacques, Rivard, Georges E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559923/ https://www.ncbi.nlm.nih.gov/pubmed/32824891 http://dx.doi.org/10.3390/ph13090201 |
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