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Beta-catenin inhibits TR4-mediated lipid accumulation in 3T3-L1 adipocytes via induction of Slug

BACKGROUND: TR4, an orphan nuclear receptor plays a key role in glucose and lipid metabolism by regulating the expression of genes involved in energy metabolism. We previously reported that overexpression of TR4 in 3T3-L1 adipocytes promotes lipid accumulation in part by facilitating fatty acid upta...

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Detalles Bibliográficos
Autores principales: Choi, Hojung, Park, Sung-Soo, Kim, Seung-Jin, Kim, Eungseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559981/
https://www.ncbi.nlm.nih.gov/pubmed/33072258
http://dx.doi.org/10.1186/s13578-020-00482-4