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Enhancer of mRNA Decapping protein 4 (EDC4) interacts with replication protein a (RPA) and contributes to Cisplatin resistance in cervical Cancer by alleviating DNA damage

BACKGROUND: Cervical cancer (CC) is the third most common gynecological malignancy around the world. Cisplatin is an effective drug, but cisplatin resistance is a vital factor limiting the clinical usage of cisplatin. Enhancer of mRNA decapping protein 4 (EDC4) is a known regulator of mRNA decapping...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoling, Zhong, Youwen, Chen, Qing, Zhang, Xin, Zhang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560020/
https://www.ncbi.nlm.nih.gov/pubmed/33054858
http://dx.doi.org/10.1186/s41065-020-00154-w