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On the History and Applications of Congenic Strains in Cryptococcus Research

Congenic strains have been utilized in numerous model organisms to determine the genetic underpinning of various phenotypic traits. Congenic strains are usually derived after 10 backcrosses to a recipient parent, at which point they are 99.95% genetically identical to the parental strain. In recent...

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Detalles Bibliográficos
Autores principales: Chadwick, Benjamin J., Lin, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560043/
https://www.ncbi.nlm.nih.gov/pubmed/32942570
http://dx.doi.org/10.3390/pathogens9090750