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Metformin Derivative HL156A Reverses Multidrug Resistance by Inhibiting HOXC6/ERK1/2 Signaling in Multidrug-Resistant Human Cancer Cells

Multidrug resistance is a significant clinical crisis in cancer treatment and has been linked to the cellular expression of multidrug efflux transporters. The aim of this study was to examine the effects and mechanisms of the metformin derivative HL156A on human multidrug resistance (MDR) cancer cel...

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Detalles Bibliográficos
Autores principales: Jeong, Yun Soo, Lam, Thuy Giang, Jeong, Seho, Ahn, Sang-Gun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560051/
https://www.ncbi.nlm.nih.gov/pubmed/32872293
http://dx.doi.org/10.3390/ph13090218