Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage

BACKGROUND: Bone marrow mesenchymal stem cells (BMSCs) have been used as important cell-based tools for clinical applications. Oxidative stress-induced apoptosis causes a low survival rate after transplantation, and the underlying mechanisms remain unknown. The endoplasmic reticulum (ER) and mitocho...

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Detalles Bibliográficos
Autores principales: Fan, Chongxi, Feng, Jianyu, Tang, Chi, Zhang, Zhengbin, Feng, Yingtong, Duan, Weixun, Zhai, Mingming, Yan, Zedong, Zhu, Liwen, Feng, Lele, Zhu, Hanzhao, Luo, Erping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560057/
https://www.ncbi.nlm.nih.gov/pubmed/33059742
http://dx.doi.org/10.1186/s13287-020-01948-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560057/
https://www.ncbi.nlm.nih.gov/pubmed/33059742
http://dx.doi.org/10.1186/s13287-020-01948-5

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