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Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage

BACKGROUND: Bone marrow mesenchymal stem cells (BMSCs) have been used as important cell-based tools for clinical applications. Oxidative stress-induced apoptosis causes a low survival rate after transplantation, and the underlying mechanisms remain unknown. The endoplasmic reticulum (ER) and mitocho...

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Detalles Bibliográficos
Autores principales:	Fan, Chongxi, Feng, Jianyu, Tang, Chi, Zhang, Zhengbin, Feng, Yingtong, Duan, Weixun, Zhai, Mingming, Yan, Zedong, Zhu, Liwen, Feng, Lele, Zhu, Hanzhao, Luo, Erping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560057/ https://www.ncbi.nlm.nih.gov/pubmed/33059742 http://dx.doi.org/10.1186/s13287-020-01948-5

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