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Accuracy and reproducibility of somatic point mutation calling in clinical-type targeted sequencing data
BACKGROUND: Treating cancer depends in part on identifying the mutations driving each patient’s disease. Many clinical laboratories are adopting high-throughput sequencing for assaying patients’ tumours, applying targeted panels to formalin-fixed paraffin-embedded tumour tissues to detect clinically...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560075/ https://www.ncbi.nlm.nih.gov/pubmed/33059707 http://dx.doi.org/10.1186/s12920-020-00803-z |