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Selection of Cryoprotectant in Lyophilization of Progesterone-Loaded Stearic Acid Solid Lipid Nanoparticles

Cryoprotectants are often required in lyophilization to reduce or eliminate agglomeration of solute or suspended materials. The aim of this study was to select a cryoprotecting agent and optimize its concentration in a solid lipid nanoparticle formulation. Progesterone-loaded stearic acid solid lipi...

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Detalles Bibliográficos
Autores principales: Amis, Timothy M., Renukuntla, Jwala, Bolla, Pradeep Kumar, Clark, Bradley A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560102/
https://www.ncbi.nlm.nih.gov/pubmed/32961738
http://dx.doi.org/10.3390/pharmaceutics12090892