In Vitro Evaluation of Farnesyltransferase Inhibitor and its Effect in Combination with 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase Inhibitor against Naegleria fowleri

Free-living amoeba Naegleria fowleri causes a rapidly fatal infection primary amebic meningoencephalitis (PAM) in children. The drug of choice in treating PAM is amphotericin B, but very few patients treated with amphotericin B have survived PAM. Therefore, development of efficient drugs is a critic...

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Detalles Bibliográficos
Autores principales: Hahn, Hye Jee, Debnath, Anjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560193/
https://www.ncbi.nlm.nih.gov/pubmed/32842691
http://dx.doi.org/10.3390/pathogens9090689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560193/
https://www.ncbi.nlm.nih.gov/pubmed/32842691
http://dx.doi.org/10.3390/pathogens9090689

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