The Alzheimer's disease‐associated C99 fragment of APP regulates cellular cholesterol trafficking

The link between cholesterol homeostasis and cleavage of the amyloid precursor protein (APP), and how this relationship relates to Alzheimer's disease (AD) pathogenesis, is still unknown. Cellular cholesterol levels are regulated through crosstalk between the plasma membrane (PM), where most ce...

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Detalles Bibliográficos
Autores principales: Montesinos, Jorge, Pera, Marta, Larrea, Delfina, Guardia‐Laguarta, Cristina, Agrawal, Rishi R, Velasco, Kevin R, Yun, Taekyung D, Stavrovskaya, Irina G, Xu, Yimeng, Koo, So Yeon, Snead, Amanda M, Sproul, Andrew A, Area‐Gomez, Estela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560219/
https://www.ncbi.nlm.nih.gov/pubmed/32865299
http://dx.doi.org/10.15252/embj.2019103791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560219/
https://www.ncbi.nlm.nih.gov/pubmed/32865299
http://dx.doi.org/10.15252/embj.2019103791

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