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Synthesis, Absolute Configuration, Antibacterial, and Antifungal Activities of Novel Benzofuryl β-Amino Alcohols

A series of new benzofuryl α-azole ketones was synthesized and reduced by asymmetric transfer hydrogenation (ATH). Novel benzofuryl β-amino alcohols bearing an imidazolyl and triazolyl substituents were obtained with excellent enantioselectivity (96–99%). The absolute configuration (R) of the produc...

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Detalles Bibliográficos
Autores principales: Tafelska-Kaczmarek, Agnieszka, Kołodziejska, Renata, Kwit, Marcin, Stasiak, Bartosz, Wypij, Magdalena, Golińska, Patrycja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560283/
https://www.ncbi.nlm.nih.gov/pubmed/32937873
http://dx.doi.org/10.3390/ma13184080