Madecassoside protects retinal pigment epithelial cells against hydrogen peroxide-induced oxidative stress and apoptosis through the activation of Nrf2/HO-1 pathway

Age-related macular degeneration (AMD) is a progressive and degenerative ocular disease associated with oxidative stress. Madecassoside (MADE) is a major bioactive triterpenoid saponin that possesses antioxidative activity. However, the role of MADE in AMD has never been investigated. In the current...

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Detalles Bibliográficos
Autores principales: Zhou, Jinzi, Chen, Fenghua, Yan, Aimin, Xia, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Therapeutics & Molecular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560535/
https://www.ncbi.nlm.nih.gov/pubmed/33000859
http://dx.doi.org/10.1042/BSR20194347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560535/
https://www.ncbi.nlm.nih.gov/pubmed/33000859
http://dx.doi.org/10.1042/BSR20194347

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