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Click CAR-T cell engineering for robustly boosting cell immunotherapy in blood and subcutaneous xenograft tumor
The adoptive transfer of chimeric antigen receptor-T (CAR-T) cells has shown remarkable clinical responses in hematologic malignancies. However, unsatisfactory curative results and side effects for tumor treatment are still unsolved problems. Herein we develop a click CAR-T cell engineering strategy...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560591/ https://www.ncbi.nlm.nih.gov/pubmed/33102938 http://dx.doi.org/10.1016/j.bioactmat.2020.09.025 |