Click CAR-T cell engineering for robustly boosting cell immunotherapy in blood and subcutaneous xenograft tumor

The adoptive transfer of chimeric antigen receptor-T (CAR-T) cells has shown remarkable clinical responses in hematologic malignancies. However, unsatisfactory curative results and side effects for tumor treatment are still unsolved problems. Herein we develop a click CAR-T cell engineering strategy...

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Detalles Bibliográficos
Autores principales: Pan, Hong, Li, Wenjun, Chen, Ze, Luo, Yingmei, He, Wei, Wang, Mengmeng, Tang, Xiaofan, He, Huamei, Liu, Lanlan, Zheng, Mingbin, Jiang, Xin, Yin, Ting, Liang, Ruijing, Ma, Yifan, Cai, Lintao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560591/
https://www.ncbi.nlm.nih.gov/pubmed/33102938
http://dx.doi.org/10.1016/j.bioactmat.2020.09.025

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